Performs custom synthesis of labelled compounds, and assessment of tests related to pharmacokinetics. ADME & Tox. Research Business of SEKISUI MEDICAL.

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Gene Polymorphism Analysis

  • Establishes a gene polymorphism system using the direct sequencing TaqMan® RT-PCR method to perform gene polymorphism analysis.
  • Provides reliable data in compliance with the GLP standards.
  • Offers analysis systems of more than 80 items that consist mainly of genes related to drug-metabolizing enzymes.

Analysis of Drug-metabolizing Enzymes

We provide information about individual differences in drug metabolism and efficacy based on the metabolic profile analysis of a candidate compound and the polymorphism analysis of related genes at an individual level. Gene polymorphism affects the expression level and function of proteins, and is related to drug efficacy and side effects. In addition to the measurement of drug blood concentrations, the analysis of gene polymorphism related to drug metabolizing enzymes and drug efficacy provide useful information for the investigation of the clinical data you obtain.

 
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