Performs custom synthesis of labelled compounds, and assessment of tests related to pharmacokinetics. ADME & Tox. Research Business of SEKISUI MEDICAL.

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Drug Concentration Determination

  • Administration to animals to measurement of samples (PK study).
    We cover from the development of a measurement system through the administration and sampling to the measurement of samples.
    We will measure samples for protein binding rate and drug interaction study.
  • Measurements of samples containing labeled compounds
    We measure samples obtained in a pharmacokinetic study with a labeled compound.
    We can perform omparative analysis with total radioactivity (LSC).
  • We can determine drug, biomarker or neutralizing antibody concentration using an immunological method (RIA, ELISA, CLEIA, FIA, etc.).

Apparatus for Concentration Determinations

LC/MS/MS

System Manufacturer
API5000 Applied Biosystems/MDS Sciex
API4000 Applied Biosystems/MDS Sciex
API3000 Applied Biosystems/MDS Sciex

HPLC

System Manufacturer
LC-10A Shimadzu
LC-10Avp Shimadzu
LC-20AD Shimadzu
 
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