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Transporter Study
We evaluate the following transporters. If you are interested in an item not listed here, please contact us.
| Tissue | Expressed transporter | Study system | |
|---|---|---|---|
| in vitro | in vivo | ||
| Liver | P-gp/MDR1 | Expressing cell | KO mouse |
| MRP2 | Expressing cell | EHBR | |
| BCRP | KO mouse | ||
| OATP8 (OATP1B3) | Oocyte | ||
| OATP1 (OATP1A2) | Oocyte | ||
| OATP2 (OATP1B1) | Oocyte | ||
| NTCP | Oocyte | ||
| Rat liver | Oatp4 (Oatp1b2) | Oocyte | |
| Kidney | P-gp/MDR1 | Expressing cell | KO mouse |
| MRP2 | Expressing cell | EHBR | |
| OAT1 | Kidney slice | ||
| OAT3 | Kidney slice | ||
| PEPT1 | Oocyte | ||
| PEPT2 | Oocyte | ||
| Small intestine | P-gp/MDR1 | Expressing cell | KO mouse |
| MRP2 | Expressing cell | EHBR | |
| BCRP | KO mouse | ||
| PEPT1 | Oocyte | ||
| Brain | P-gp/MDR1 | Expressing cell | KO mouse |
| BCRP | KO mouse | ||
| OATP1 (OATP1A2) | Oocyte | ||
| OAT3 | Kidney slice | ||
| Various tissues | OCT3 | Oocyte | |
