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Digoxin Kit
DRI Digoxin
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Reference Data
Precision (within-run)
(ng/mL)
| N | Mean | S.D. | C.V. (%) | Min. | Max. | |
|---|---|---|---|---|---|---|
| Sample 1 | 20 | 0.80 | 0.02 | 2.81 | 0.7 | 0.8 |
| Sample 2 | 20 | 1.99 | 0.05 | 2.47 | 1.9 | 2.1 |
| Sample 3 | 20 | 3.16 | 0.05 | 1.62 | 3.1 | 3.2 |
Correlation
- Measurement range: 0.1-5ng/mL
- Concentration range for therapy: 0.9-2ng/mL*
Interference
(ng/mL)
| Spiked substance | Concentration | Measurement | |
|---|---|---|---|
| Base serum | Added serum | ||
| Free bilirubin | 20mg/dL | 2.0 | 1.9 |
| Conjugated bilirubin | 20mg/dL | 2.0 | 2.0 |
| Hemoglobin | 500mg/dL | 2.0 | 2.0 |
| Lipemia (Formazin turbidity unit) | 3,000 | 1.9 | 2.0 |
Cross reactivity
(ng/mL)
| Substance | Concentration (ng/mL) | Cross reaction rate (%) |
|---|---|---|
| Digoxigenin | 50 | 3.6 |
| Digoxigenin bis-digitoxoside | 5 | 108.0 |
| Digoxigenin mono-digitoxoside | 5 | 82.0 |
| Digitoxin | 50 | 4.4 |
| Digitoxigenin | 500 | 0.7 |
| D-(+)-Digitoxose | 10,000 | 0.0 |
| Gitoxin | 150 | 0.5 |
The following substances didn't show cross-reactivity to the measurement of Digoxin at the following concentrations.
(µg/mL)
| Substance | Concentration |
|---|---|
| Acetaminophen | 1,000 |
| Cortisone | 10 |
| Estriol | 10 |
| Phenitoin | 100 |
| Prednisone | 10 |
| Progesterone | 10 |
| Secobarbital | 100 |
| Testosterone | 5 |
| 17-α-OH Progesterone | 10 |
| Quinidine | 100 |
| Hydrochlorothiazide | 100 |
(µg/mL)
| Substance | Concentration |
|---|---|
| Cortisol | 10 |
| Dehydroisoandrosterone | 10 |
| Lidocaine | 100 |
| Prednisolone | 10 |
| Propranolol | 100 |
| Spironolactone | 10 |
| Phenobarbital | 100 |
| Procaine amide | 100 |
| 11-OH-Progesterone | 10 |
| Ouabain octahydrate | 0.15 |
| Furosemide | 50 |
References
*Jogestrand T,et.al:Am.Heart J. 117, 1076 (1989)
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