Drug Concentration Determination

  • Administration to animals to measurement of samples (PK study).
    We cover from the development of a measurement system through the administration and sampling to the measurement of samples.
    We will measure samples for protein binding rate and drug interaction study.
  • Measurements of samples containing labeled compounds
    We measure samples obtained in a pharmacokinetic study with a labeled compound.
    We can perform omparative analysis with total radioactivity (LSC).
  • We can determine drug, biomarker or neutralizing antibody concentration using an immunological method (RIA, ELISA, CLEIA, FIA, etc.).

Apparatus for Concentration Determinations

LC/MS/MS

  • QTRAP 5500
  • 4000 QTRAP
  • API 5000
  • API 4000
  • Xevo TQ-XS (with Micro LC and Ionkey)

HPLC

  • POWERSCAN HT
  • EnVision
  • Mithras LB940-BA
  • Bio-Plex 200
  • MESO QuickPlex SQ 120