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Reference Data (1)
Control Your LDL Cholesterol Level
Patients with diabetes have a high rate of macrovascular diseases, such as coronary artery disease. According to results of a large-scale intervention test, not only blood glucose control but also lipid control are important in preventing patients with diabetes from developing macrovascular diseases. The major cause of death in patients with type 2 diabetes is not the three major complications (retinopathy, nephropathy and peripheral nerve disorder) but macrovascular diseases.
Risk factors for coronary artery diseases for patients with type 2 diabetes (according to UKPDS*)
- No. 1 factor : LDL cholesterol
- No. 2 factor : HDL cholesterol
- No. 3 factor : HbA1c
According to the UKPDS, LDL cholesterol and HDL cholesterol rank number 1 and 2, respectively, as risk factors for coronary artery diseases in patients with type 2 diabetes. At the very least, the study suggests that hyperlipidemia has a greater effect on longevity than hyperglycemia.
The relationship between diabetes and myocardial infarction is shown above. According to the data, diabetes itself is a great risk for myocardial infarction; the risk level is nearly the same as that for nondiabetic patients with a history of myocardial infarction.
- *United Kingdom Prospective Diabetes Study
Reagent Cholestest LDL for direct method for LDL cholesterol measurement
Comparison between ultracentrifugation and direct methods
Sixty to seventy percent of patients with diabetes develop hyperlipemia (diabetes complicated hyperlipemia), and develop hypertriglyceridemia associated with an increase in remnants. Cholestest LDL is unaffected by high levels of TG, and thereby allows accurate measurement in patients with diabetic hyperlipemia or even in samples collected after meals.
About test items
LDL-Cholesterol, the so-called "bad" cholesterol, is said to be contained in large quantities in blood of patients with cardiac or cerebral vascular diseases, and increases with age.
"Cholestest" is a trademark or registered trademark of SEKISUI MEDICAL CO., LTD. in Japan and/or other countries.
We prepared this page for medical staff (doctors, dentists, pharmacists, clinical laboratory technicians, nurses, etc.) in Japan to ensure the correct use of our products. You should be aware that the information provided is not intended for overseas medical staff and the general public.